Convert from the mass of one substance to the mass of another using a balanced equation, molar mass, and mole ratios together in a single multi-step calculation.
Real laboratory measurements are made in grams, not moles, so the most practical stoichiometry problems start and end in mass. The path has three steps, each one a skill you already have: convert the given mass to moles using its molar mass, convert those moles to moles of the target substance using the mole ratio from the balanced equation, then convert those moles to a mass using the target substance's molar mass.
Written as a chain: grams (given) -> moles (given) -> moles (target) -> grams (target). Skipping the middle "moles" step and trying to relate two substances' masses directly is not possible, since the balanced equation only ever tells you a relationship in MOLES, never in grams directly.
Mastery looks like: They correctly complete a full mass-to-mass stoichiometry calculation, converting grams to moles, applying the correct mole ratio, and converting back to grams.
Common stumbles: Skipping the grams-to-moles conversion and trying to apply the mole ratio directly to grams; using the wrong substance's molar mass in the final conversion step.