Convert between moles and number of particles using Avogadro's number, and explain why chemists need the mole as a counting unit.
Atoms and molecules are far too small and far too numerous to count one at a time, so chemists count them in bulk using a special counting unit called the mole -- exactly like a "dozen" always means 12, no matter what you are counting, a mole always means 6.022 x 10^23 of whatever you are counting. That number, 6.022 x 10^23, is Avogadro's number, and it was chosen specifically so that one mole of atoms would have a mass in grams equal to that element's atomic mass in amu -- a connection that makes the mole the bridge between counting particles and weighing them on a balance.
Converting between moles and particles uses Avogadro's number as a conversion factor, exactly like the metric conversions from earlier this year: moles x (6.022 x 10^23 particles / 1 mole) gives particles, and particles x (1 mole / 6.022 x 10^23 particles) gives moles.
Mastery looks like: They correctly convert between moles and number of particles using Avogadro's number in either direction, with correct sig figs.
Common stumbles: Multiplying by Avogadro's number when the problem actually requires dividing (going from particles back to moles); losing track of the power of 10 when multiplying two numbers in scientific notation.